Monday, 24 November 2008

What are the methods for infering genetic interactions?

BioGRID is an interaction database, and they catalogue interactions by (among other things) the class of experiment that discovered them. See http://wiki.thebiogrid.org/doku.php/experimental_systems#genetic_interactions



Other than that, you should look at recent reviews and publications, but you will easily get lost unless you figure out some important particulars, like:



  • What species? Yeast, worm, human, cell line?

  • What sort of interaction? Synthetic lethality? Complicated, fancy epistasis?

  • How much? Genome-wide? 2-3 genes?

No comments:

Post a Comment