sometimes you can get these spike artifacts from the microlenses over the CCD's sensor array as well.
also if your CCD does not have antiblooming logic, a very bright star can cause neighboring pixels to saturate as they are being read out, leading to a "spike" only along the readout axis. here's a good document with some common artifacts, from the hubble team:
HandoutIIIc.
the spikes in the OP's image are likely caused by the spider vanes which hold the secondary mirror in place, as Russell says.
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