Suppose $G$ a reductive Lie group with finitely many connected components, and suppose in addition that the connected component $G^0$ of the identity can be expressed as a finite cover of a linear Lie group. Denote by $mathfrak{g}$ the complexified Lie algebra, and denote by $K$ a maximal compact in the complexification of $G$.
Denote by $mathbf{HC}(mathfrak{g},K)$ the category of admissible $(mathfrak{g},K)$-modules or (Harish Chandra modules), and $(mathfrak{g},K)$-module homomorphisms. Denote by $mathbf{Rep}(G)$ the category of admissible representations of finite length (on complete locally convex Hausdorff topological vector spaces), with continuous linear $G$-maps.
The Harish Chandra functor $mathcal{M}colonmathbf{Rep}(G)tomathbf{HC}(mathfrak{g},K)$ assigns to any admissible representation $V$ the Harish Chandra module of $K$-finite vectors of $V$. This is a faithful, exact functor. Let us call an exact functor $mathcal{G}colonmathbf{HC}(mathfrak{g},K)tomathbf{Rep}(G)$ along with a comparison isomorphism $eta_{mathcal{G}}colonmathcal{M}circmathcal{G}simeqmathrm{id}$ a globalization functor.
Our first observation is that globalization functors exist.
Theorem. [Casselman-Wallach] The restriction of $mathcal{M}$ to the full subcategory of smooth admissible Fréchet spaces is an equivalence. Moreover, for any Harish Chandra module $M$, the essentially unique smooth admissible representation $(pi,V)$ such that $Mcongmathcal{M}(pi,V)$ has the property $pi(mathcal{S}(G))M=V$, where $mathcal{S}(G)$ is the Schwartz algebra of $G$.
If we do not restrict $mathcal{M}$ to smooth admissible Fréchet spaces, then we have a minimal globalization and a maximal one.
Theorem. [Kashiwara-Schmid] $mathcal{M}$ admits both a left adjoint $mathcal{G}_0$ and right adjoint $mathcal{G}_{infty}$, and the counit and unit give these functors the structure of globalization functors.
Construction. Here, briefly, are descriptions of the minimal and maximal globalizations. The minimal globalization is
$$mathcal{G}_0=textit{Dist}_c(G)otimes_{U(mathfrak{g})}-$$
where $textit{Dist}_c(G)$ denotes the space of compactly supported distributions on $G$, and the maximal one is
$$mathcal{G}_{infty}=mathrm{Hom}_{U(mathfrak{g})}((-)^{vee},C^{infty}(G))$$
where $M^{vee}$ is the dual Harish Chandra module of $M$ (i.e., the $K$-finite vectors of the algebraic dual of $M$).
For any Harish Chandra module $M$, the minimal globalization $mathcal{G}_0(M)$ is a dual Fréchet nuclear space, and the maximal globalization $mathcal{G}_{infty}(M)$ is a Fréchet nuclear space.
Example. If $Psubset G$ is a parabolic subgroup, then the space $L^2(G/P)$ of $L^2$-functions on the homogeneous space $G/P$ is an admissible representation, and $M=mathcal{M}(L^2(G/P))$ is a particularly interesting Harish Chandra module. In this case, one may identify $mathcal{G}_0(M)$ with the real analytic functions on $G/P$, and one may identify $mathcal{G}_{infty}(M)$ with the hyperfunctions on $G/P$.
[I think other globalizations with different properties are known or expected; I don't yet know much about these, however.]
Consider the category $mathbf{Glob}(G)$ of globalization functors for $G$; morphisms $mathcal{G}'tomathcal{G}$ are natural transformations that are required to be compatible with the comparison isomorphisms $eta_{mathcal{G}'}$ and $eta_{mathcal{G}}$. Since $mathcal{M}$ is faithful, this category is actually a poset, and it has both an inf and a sup, namely $mathcal{G}_0$ and $mathcal{G}_{infty}$. This is the poset of globalizations for $G$.
I'd like to know more about the structure of the poset $mathbf{Glob}(G)$ — really, anything at all, but let me ask the following concrete question.
Question. Does every finite collection of elements of $mathbf{Glob}(G)$ admit both an inf and a sup?
[Added later]
Emerton (below) mentions a geometric picture that appears to be very well adapted to the study of our poset $mathbf{Glob}(G)$. Let me at introduce the main ideas of the objects of interest, and what I learned about our poset. [What I'm going to say was essentially outlined by Kashiwara in 1987.] For this, we probably need to assume that $G$ is connected.
Notation. Let $X$ be the flag manifold of the complexification of $G$. Let $lambdainmathfrak{h}^{vee}$ be a dominant element of the dual space of the universal Cartan; for simplicity, let's assume that it is regular. Now one can define the twisted equivariant bounded derived categories $D^b_G(X)_{-lambda}$ and $D^b_K(X)_{-lambda}$ of constructible sheaves on $X$. Now let $mathbf{Glob}(G,lambda)$ denote the poset of globalizations for admissible representations with infinitesimal character $chi_{lambda}$, so the objects are exact functors $mathcal{G}colonmathbf{HC}(mathfrak{g},K)_{chi_{lambda}}tomathbf{Rep}(G)_{chi_{lambda}}$ equipped with natural isomorphisms $eta_{mathcal{G}}:mathcal{M}circmathcal{G}simeqmathrm{id}$.
Matsuki correspondence. [Mirkovic-Uzawa-Vilonen] There is a canonical equivalence $Phicolon D^b_G(X)_{-lambda}simeq D^b_K(X)_{-lambda}$. The perverse t-structure on the latter can be lifted along this correspondence to obtain a t-structure on $D^b_G(X)_{-lambda}$ as well. The Matsuki correspondence then restricts to an equivalence $Phicolon P_G(X)_{-lambda}simeq P_K(X)_{-lambda}$ between the corresponding hearts.
Beilinson-Bernstein construction. There is a canonical equivalence $alphacolon P_K(X)_{-lambda}simeqmathbf{HC}(mathfrak{g},K)_{chi_{lambda}}$, given by Riemann-Hilbert, followed by taking cohomology. [If $lambda$ is not regular, then this isn't quite an equivalence.]
Now we deduce a geometric description of an object of $mathbf{Glob}(G,lambda)$ as an exact functor $mathcal{H}colon P_G(X)_{-lambda}tomathbf{Rep}(G)_{chi_{lambda}}$ equipped with a natural isomorphism $mathcal{M}circmathcal{H}simeqalphacircPhi$, or equivalently, as a suitably t-exact functor $mathcal{H}colon D^b_G(X)_{-lambda}to D^bmathbf{Rep}(G)_{chi_{lambda}}$ equipped with a functorial identification between the (complex of) Harish Chandra module(s) of $K$-finite vectors of $mathcal{H}(F)$ and $mathrm{RHom}(mathbf{D}Phi F,mathcal{O}_X(lambda))$ for any $Fin D^b_G(X)_{-lambda}$. In particular, as Emerton observes, the maximal and minimal globalizations can be expressed as
$$mathcal{H}_{infty}(F)=mathrm{RHom}(mathbf{D}F,mathcal{O}_X(lambda))$$
and
$$mathcal{H}_0(F)=Fotimes^Lmathcal{O}_X(lambda)$$
Note that Verdier duality gives rise to an anti-involution $mathcal{H}mapsto(mathcal{H}circmathbf{D})^{vee}$ of the poset $mathbf{Glob}(G,lambda)$; in particular, it exchanges $mathcal{H}_{infty}$ and $mathcal{H}_0$.
I now expect that one can show the following (though I don't claim to have thought about this point carefully enough to call it a proposition).
Conjecture. All globalization functors are representable. That is, every element of $mathbf{Glob}(G,lambda)$ is of the form $mathrm{RHom}(mathbf{D}(-),E)$ for some object $Ein D^b_G(X)_{-lambda}$.
Question. Can one characterize those objects $Ein D^b_G(X)_{-lambda}$ such that the functor $mathrm{RHom}(mathbf{D}(-),E)$ is a globalization functor? Given a map between any two of these, under what circumstances do they induce a morphism of globalization functors (as defined above)?
In particular, note that if my expectation holds, then one should be able to find a copy of the poset $mathbf{Glob}(G,lambda)$ embedded in $D^b_G(X)_{-lambda}$.