I was under the impression (q.v the Impossible Astronaut) that the Silence needed the suit to physically control River Song. They're aware of the events surrounding his death; e.g. that he's shot by River Song at Lake Silencio on the date in question and must have been quite surprised to find that she had no intention of doing so.
Their reaction was to travel further back into time and guide the development of the human race to the point that they'd developed a space suit capable of being used as a physical control device, turning her into a 'people puppet'
In the episode 'The Impossible Astronaut' River Song says to the Doctor at the moment of his apparent death: "I can't stop it - the suit's in control"
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